HbA1c is not recommended as a screening test for diabetes in cystic fibrosis

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Serum pancreatic lipase as a screening test for cystic fibrosis.

Pancreatic lipase catalyses the hydrolysis of emulsified triglycerides to form a transparent solution of monoglycerides and fatty acids. Levels of serum pancreatic lipase were measured in neonates known to have cystic fibrosis and compared with levels in control infants. During the first weeks of life infants with cystic fibrosis had raised serum pancreatic lipase values in parallel with raised...

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Serum pancreatic lipase as a screening test for cystic fibrosis

Crossley J R, Elliott R B, Smith P A. Dried-blood spot screening for cystic fibrosis in the newborn. Lancet 1979; i: 472-4. 2 Crossley J R, Smith P A, Edgar B W, Gluckman P D, Elliott R B. Neonatal screening for cystic fibrosis using immunoreactive trypsin assay in dried-blood spots. Clin ChimActa 1981; 113: 111-21. 3 Adriaenssens K, Janssens H, Van Soom H. Letter: Two tier screen for cystic fi...

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Improving screening for cystic fibrosis-related diabetes at a pediatric cystic fibrosis program.

OBJECTIVE Despite guidelines recommending an annual oral glucose tolerance test (OGTT) for all patients with cystic fibrosis (CF) aged ≥ 10 years, screening rates for cystic fibrosis-related diabetes (CFRD) remained low at our center. The aim of this project was to implement an outpatient system to provide effective, evidence-based screening for CFRD at a pediatric CF program. METHODS Develop...

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Screening for cystic fibrosis-related diabetes: a systematic review.

BACKGROUND Cystic fibrosis (CF) is an inherited disease that leads to damage to lungs, pancreas and other organs. Most people with CF die prematurely from lung disease, but survival has improved markedly over the decades and it is estimated that children born with CF now will live to an average age of 50 years. CF-related diabetes (CFRD) is due to damage to the pancreas, which, over time, loses...

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Cystic Fibrosis-Related Diabetes: Screening and Diagnosis

CFRD — Cystic fibrosis-related diabetes — is the most prevalent extrapulmonary complication of cystic fibrosis and is associated with decline in pulmonary function, poor nutritional status, and greater mortality. Although our general understanding of CFRD has increased, difficult areas remain in its pathophysiology, screening, diagnosis, and management that require further research and developm...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2000

ISSN: 0149-5992,1935-5548

DOI: 10.2337/diacare.23.1.126b